<i>Morella esculenta<_i> (Buch.-Ham. ex D. Don) I. M. Turner

By Targets:	Antibiotic (1) Bacterial (1) Biochemical Assay Reagents (1) CCR (1) COX (2) Drug Metabolite (1) Endogenous Metabolite (2) Fungal (1) Glutaminase (2) Influenza Virus (1) Isotope-Labeled Compounds (1) NF-κB (2)
By Research Areas:	Cancer (5) Cardiovascular Disease (2) Endocrinology (1) Infection (7) Inflammation/Immunology (5) Metabolic Disease (2) Neurological Disease (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N5079

Lotaustralin

Others Others

Lotaustralin is a cyanogenic glucoside isolated from Manihot esculenta .

Lotaustralin	Others	Others
Lotaustralin is a cyanogenic glucoside isolated from Manihot esculenta .

HY-N11484

5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside	Others	Others
5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside is a natural product that can be isolated from the root of Scutellaria repens Buch.-Ham. ex D. Don .

HY-153151

*Fmoc-DON-Boc*	Others	Cancer
Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist .

HY-N11066

Anhuienside F

Others Others

Anhuienside F is a natural product that can be isolated from the root of Anemone vitifolia Buch.-Ham .
HY-125121

Esculentoside C

Biochemical Assay Reagents Others

Esculentoside C is a triterpene saponin. Esculentoside C can be obtained from the root of Phytolacca esculenta .

Anhuienside F	Others	Others
Anhuienside F is a natural product that can be isolated from the root of Anemone vitifolia Buch.-Ham .

Esculentoside C	Biochemical Assay Reagents	Others
Esculentoside C is a triterpene saponin. Esculentoside C can be obtained from the root of Phytolacca esculenta .

HY-N11678

Deoxynivalenol-3-β-D-glucoside Don-3-β-D-glucoside; Deoxynivalenol 3-glucoside	Drug Metabolite	Metabolic Disease
Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a plant metabolite of the Fusarium mycotoxin Deoxynivalenol (HY-N6684). Deoxynivalenol-3-β-D-glucoside exhibits lower toxicity than Deoxynivalenol in vitro and in vivo .

HY-N10860

5-O-beta-D-Glucopyranosylmyricanol	Others	Others
5-O-beta-D-Glucopyranosylmyricanol is a diarylheptane compound isolated from Myrica esculenta that has a weak inhibitory effect on angiotensin-converting enzyme (ACE) .

HY-122218

JHU-083 4 Publications Verification	Glutaminase	Neurological Disease
JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b ⁺ cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals .

HY-108357

6-Diazo-5-oxo-L-nor-Leucine Maximum Cited Publications 7 Publications Verification L-6-Diazo-5-oxonorleucine; Don	Glutaminase Bacterial Influenza Virus Antibiotic	Infection Cancer
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .

HY-N4094

Morellic acid

Others Inflammation/Immunology

Morellic acid is isolated from Garcinia Morella with an antiangiogenic activity .
HY-N1057

Plantarenaloside

Yuheinoside

Plantarenaloside is an iridoid glucoside that can be isolated from Leucocarpus perfoliatus G. DON .
HY-N3371

Longikaurin E

(-)-Longikaurin E
Others Others

Longikaurin E is a diterpenoids compound isolated from the leaves of Rabdosia ternifolia (D. Don) .
HY-N7521

Procyanidin C2

Procyanidine C2
Others Others

Procyanidin C2 is a phenol glycoside derived from Fagopyrum dibotrys (D. Don) Hara .

Morellic acid	Others	Inflammation/Immunology
Morellic acid is isolated from Garcinia Morella with an antiangiogenic activity .

Plantarenaloside Yuheinoside
Plantarenaloside is an iridoid glucoside that can be isolated from Leucocarpus perfoliatus G. DON .

Longikaurin E (-)-Longikaurin E	Others	Others
Longikaurin E is a diterpenoids compound isolated from the leaves of Rabdosia ternifolia (D. Don) .

Procyanidin C2 Procyanidine C2	Others	Others
Procyanidin C2 is a phenol glycoside derived from Fagopyrum dibotrys (D. Don) Hara .

HY-N6685

3-Acetyldeoxynivalenol	Others	Cardiovascular Disease
3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .

HY-N1623

1-Hydroxy-2,3,4,7-tetramethoxyxanthone	Endogenous Metabolite	Metabolic Disease
1-Hydroxy-2,3,4,7-tetramethoxyxanthone is a metabolite of xanthone that can be found in Halenia elliptica D. Don .

HY-N3866

Esculentic acid	COX	Inflammation/Immunology
Esculentic acid is a selective COX-2 inhibitor and has anti-inflammatory effect. Esculentic acid is a pentacyclic triterpenoid that can be extracted from the Chinese herb Phytolacca esculenta .

HY-N3706

Dehydro-α-lapachone	Fungal	Infection
Dehydro-α-lapachone can be isolated from the methanol extract of stems of Catalpa ovata G Don. Dehydro-α-lapachone inhibits mycelial growth of Botrytis cinerea with IC₅₀ value 0.41 mg/L .

HY-N1390

Syringaldehyde
Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis . Syringaldehyde moderately inhibits COX-2 activity with an IC₅₀ of 3.5 μg/mL . Anti-hyperglycemic and anti-inflammatory activities .

HY-N6685S1

3-Acetyldeoxynivalenol-13C17	Isotope-Labeled Compounds	Cardiovascular Disease
3-Acetyldeoxynivalenol- ¹³C₁₇ is the ¹³C labeled 3-Acetyldeoxynivalenol (HY-N6685) . 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .

HY-N3552

Catalposide	NF-κB	Inflammation/Immunology
Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages .

HY-128775

JHU395	Others	Cancer
JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST .

HY-P99253

Mogamulizumab KW-0761	CCR	Inflammation/Immunology Cancer
Mogamulizumab (KW-0761) is a recombinant anti-CCR4 monoclonal antibody (MAb). Mogamulizumab can eliminate tumor cells by antibody-dependent cellular cytotoxicity (ADCC). Mogamulizumab can be used in the research of cancers, adult T-cell leukemia/lymphoma (ATLL), cutaneous T-cell lymphoma (CTCL) .

HY-N2205

Esculentoside H
Esculentoside H (EsH) is a saponin isolated from the root extract of perennial plant Phytolacca esculenta . Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease . Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression .

HY-N0632

Esculentoside A 2 Publications Verification	COX NF-κB	Inflammation/Immunology
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .

HY-155535

17β-HSD10-IN-2	Endogenous Metabolite	Neurological Disease
17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor，targeting to 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10)，a multifunctional mitochondrial enzyme. 17β-HSD10-IN-2 don't lead to mitochondrial off-targets and cytotoxic or neurotoxic effects. 17β-HSD10 inhibitors can be used for research in Alzheimer's disease (AD) and hormone-dependent cancer .

Cat. No.	Product Name	Type

HY-150287

Insulin-Transferrin-Selenium, 100X ITS-G	Biochemical Assay Reagents
Insulin-Transferrin-Selenium, 100X (ITS-G) is a mixture of Insulin, transferrin, and sodium selenite that is a general supplement designed for use in classic media such as DMEM, RPMI-1640, and nutrient media such as Ham's F-12, DMEM/F-12 . Insulin-Transferrin-Seleniu is added to basal medium to reduce the amount of fetal calf serum required to culture cells.

Cat. No.	Product Name	Target	Research Area

HY-P5659

Brevinin-1

Peptides Infection

Brevinin-1 is an antimicrobial peptide derived from the skin secretions of Rana esculenta .
HY-P5660

Brevinin-2

Peptides Infection

Brevinin-2 is an antimicrobial peptide derived from the skin secretions of Rana esculenta .
HY-P5662

Brevinin-2EC

Peptides Infection

Brevinin-2EC is an antimicrobial peptide derived from the skin secretions of Rana esculenta .
HY-P5656

Brevinin-1Ea

Peptides Infection

Brevinin-1Ea is an antimicrobial peptide derived from the skin secretions of Rana esculenta .
HY-P5658

Brevinin-1E

Peptides Infection

Brevinin-1E is an antimicrobial peptide derived from the skin secretions of Rana esculenta .

Brevinin-1	Peptides	Infection
Brevinin-1 is an antimicrobial peptide derived from the skin secretions of Rana esculenta .

Brevinin-2	Peptides	Infection
Brevinin-2 is an antimicrobial peptide derived from the skin secretions of Rana esculenta .

Brevinin-2EC	Peptides	Infection
Brevinin-2EC is an antimicrobial peptide derived from the skin secretions of Rana esculenta .

Brevinin-1Ea	Peptides	Infection
Brevinin-1Ea is an antimicrobial peptide derived from the skin secretions of Rana esculenta .

Brevinin-1E	Peptides	Infection
Brevinin-1E is an antimicrobial peptide derived from the skin secretions of Rana esculenta .

Cat. No.	Product Name	Target	Research Area

HY-P99176

ATG-031 1 Publications Verification	Inhibitory Antibodies	Cancer
ATG-031 is a humanised anti-CD24 monoclonal antibody. ATG-031 effectively stimulates macrophage-mediated phagocytosis and induces cancer cell destruction by blocking the "don't eat me" signals that characterize the growth of many cancers. ATG-031 can be used in the study of haematological malignancies as well as solid tumours.

HY-P99253

Mogamulizumab KW-0761	CCR	Inflammation/Immunology Cancer
Mogamulizumab (KW-0761) is a recombinant anti-CCR4 monoclonal antibody (MAb). Mogamulizumab can eliminate tumor cells by antibody-dependent cellular cytotoxicity (ADCC). Mogamulizumab can be used in the research of cancers, adult T-cell leukemia/lymphoma (ATLL), cutaneous T-cell lymphoma (CTCL) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N5079

Lotaustralin	Alkaloids Structural Classification Classification of Application Fields Rhodiola rosea Linn. Source classification Crassulaceae Other Diseases Plants Disease Research Fields	Others
Lotaustralin is a cyanogenic glucoside isolated from Manihot esculenta .

HY-N11484

5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside	Structural Classification Flavonoids Scutellaria baicalensis Georgi Flavones Labiatae Source classification Plants	Others
5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside is a natural product that can be isolated from the root of Scutellaria repens Buch.-Ham. ex D. Don .

HY-N11066

Anhuienside F	Anemone vitifolia Buch.-Ham. Triterpenes Structural Classification Terpenoids Source classification Ranunculaceae Plants	Others
Anhuienside F is a natural product that can be isolated from the root of Anemone vitifolia Buch.-Ham .

HY-125121

Esculentoside C	Triterpenes Structural Classification Terpenoids Source classification Phytolacca acinosa Roxb. Plants Phytolaccaceae	Biochemical Assay Reagents
Esculentoside C is a triterpene saponin. Esculentoside C can be obtained from the root of Phytolacca esculenta .

HY-N11678

Deoxynivalenol-3-β-D-glucoside Don-3-β-D-glucoside; Deoxynivalenol 3-glucoside	Structural Classification Natural Products Microorganisms Source classification	Drug Metabolite
Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a plant metabolite of the Fusarium mycotoxin Deoxynivalenol (HY-N6684). Deoxynivalenol-3-β-D-glucoside exhibits lower toxicity than Deoxynivalenol in vitro and in vivo .

HY-N10860

5-O-beta-D-Glucopyranosylmyricanol	Structural Classification Other Monoterpenes Terpenoids Source classification Morella esculenta (Buch.-Ham. ex D. Don) I. M. Turner Plants Myricaceae	Others
5-O-beta-D-Glucopyranosylmyricanol is a diarylheptane compound isolated from Myrica esculenta that has a weak inhibitory effect on angiotensin-converting enzyme (ACE) .

HY-N4094

Morellic acid	Natural Products Monophenols other families Classification of Application Fields Source classification Phenols Plants Disease Research Fields Inflammation/Immunology	Others
Morellic acid is isolated from Garcinia Morella with an antiangiogenic activity .

HY-N3371

Longikaurin E (-)-Longikaurin E	Artemisia selengensis Turcz. ex Bess. Classification of Application Fields Terpenoids Labiatae Source classification Other Diseases Diterpenoids Plants Disease Research Fields	Others
Longikaurin E is a diterpenoids compound isolated from the leaves of Rabdosia ternifolia (D. Don) .

HY-N7521

Procyanidin C2 Procyanidine C2	Structural Classification Polygonaceae Source classification Phenols Polyphenols Fagopyrum dibotrys (D. Don) Hara Plants	Others
Procyanidin C2 is a phenol glycoside derived from Fagopyrum dibotrys (D. Don) Hara .

HY-N6685

3-Acetyldeoxynivalenol	Cardiovascular Disease Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Others
3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .

HY-N1623

1-Hydroxy-2,3,4,7-tetramethoxyxanthone	Structural Classification Halenia elliptica D. Don Flavonoids Xanthones Source classification Gentianaceae Phenols Plants	Endogenous Metabolite
1-Hydroxy-2,3,4,7-tetramethoxyxanthone is a metabolite of xanthone that can be found in Halenia elliptica D. Don .

HY-N3866

Esculentic acid	Triterpenes Structural Classification Terpenoids Labiatae Source classification Plants Vachellia nilotica (L.) P. J. H. Hurter & Mabb.	COX
Esculentic acid is a selective COX-2 inhibitor and has anti-inflammatory effect. Esculentic acid is a pentacyclic triterpenoid that can be extracted from the Chinese herb Phytolacca esculenta .

HY-N3706

Dehydro-α-lapachone	Structural Classification Natural Products Catalpa ovata G. Don Source classification Plants Bignoniaceae	Fungal
Dehydro-α-lapachone can be isolated from the methanol extract of stems of Catalpa ovata G Don. Dehydro-α-lapachone inhibits mycelial growth of Botrytis cinerea with IC₅₀ value 0.41 mg/L .

HY-N3552

Catalposide	Other Terpenoids Catalpa ovata G. Don Monophenols Classification of Application Fields Terpenoids Source classification Phenols Plants Bignoniaceae Disease Research Fields Inflammation/Immunology	NF-κB
Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages .

HY-N0632

Esculentoside A 2 Publications Verification	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Phytolacca acinosa Roxb. Plants Inflammation/Immunology Disease Research Fields Phytolaccaceae	COX NF-κB
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .

HY-155535

17β-HSD10-IN-2	Structural Classification Monophenols Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
17β-HSD10-IN-2 (compound 11) is a benzothiazolylurea-based inhibitor，targeting to 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10)，a multifunctional mitochondrial enzyme. 17β-HSD10-IN-2 don't lead to mitochondrial off-targets and cytotoxic or neurotoxic effects. 17β-HSD10 inhibitors can be used for research in Alzheimer's disease (AD) and hormone-dependent cancer .

Cat. No.	Compare	Product Name	Species	Source

HY-P74682

	Neuregulin-2/NRG2 Protein, Human (HEK293, His) Pro-neuregulin-2; Pro-NRG2; Neuregulin-2; Don-1; NTAK; NRG-2	Human	HEK293
	Neuregulin-2/NRG2 protein serves as a direct ligand for the ERBB3 and ERBB4 tyrosine kinase receptors, initiating ligand-stimulated tyrosine phosphorylation and activation of these receptors. At the same time, NRG2 simultaneously recruits ERBB1 and ERBB2 coreceptors, possibly promoting heterodimerization with the EGF receptor. Neuregulin-2/NRG2 Protein, Human (HEK293, His) is the recombinant human-derived Neuregulin-2/NRG2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Neuregulin-2/NRG2 Protein, Human (HEK293, His) is 293 a.a., with molecular weight of ~34 kDa.

Cat. No.	Product Name	Chemical Structure

HY-N6685S1

3-Acetyldeoxynivalenol-13C17
3-Acetyldeoxynivalenol- ¹³C₁₇ is the ¹³C labeled 3-Acetyldeoxynivalenol (HY-N6685) . 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

<i>Morella esculenta<_i> (Buch.-Ham. ex D. Don) I. M. Turner

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Natural
Products